To paraphrase the great Paul F. Tompkins, Takeshi's Challenge is a video game that is actively defying you to like it.

The League for Spiritual Discovery, an LSD-based meditation center in New York City, in 1967 Ben Martin / Getty Images Bicycle Day, celebrated annually on April 19, commemorates the world’s first ...

Over dinner recently a top agent told us they’d attended a party the evening before hosted by an A-list comedian’s company, and at the entrance were two waiters holding mysterious little spritz ...

How do you know anything is real? Some things you can see directly, like your fingers. Other things, like your chin, you need a mirror or a camera to see. Other things can’t be seen, but you believe ...

Two major trials investigating the potential of the psychedelic drug LSD for reducing anxiety are set to conclude in 2026. Scientists are feeling positive after the drug’s success in an earlier-stage ...

In 1943, biochemist Albert Hoffman accidentally ingested a chemical that he had synthesized from a fungus and discovered that it created hallucinations. The mind-bending chemical was lysergic acid ...

He helped make and distribute millions of LSD tablets in the 1970s. After seven years in prison, he ran mountain climbing expeditions in the Himalayas. By Richard Sandomir Henry Todd, a Scotsman who ...

University of Auckland researchers report that an 8-week, twice-weekly LSD microdosing regimen for major depressive disorder was feasible and well-tolerated, with Montgomery-Åsberg Depression Rating ...

The true nature of our universe as been an open debate for millennia, and recently, scientists and philosophers have pondered whether it might be a hyper-realistic simulation perpetuated by some super ...

LSD reduced symptoms of anxiety in a midstage study published Thursday, paving the way for additional testing and possible medical approval of a psychedelic drug that has been banned in the U.S. for ...

A mid-stage study of a pharmaceutical version of the psychedelic LSD reported the drug might help alleviate anxiety symptoms for up to three months, advancing a potential treatment for the most common ...