HIV-1 envelope glycoprotein (Env), a gp120–gp41 trimer, undergoes coordinated conformational changes that drive membrane fusion and allow immune evasion by transiently concealing ...

Researchers at Ben-Gurion University of the Negev have identified simple rules that explain how complex protein structures ...

For structural biologists, the molecular mapping of proteins is critical to figuring out their structure and function. But doing so takes patience and persistence. X-ray crystallography involves ...

Humans adjust to changes in temperature by putting on a sweater or taking off layers. Plants adjust to temperature changes, ...

Proteins are the molecular workhorses of cells. To understand their functions, scientists soon realized that they had to figure out proteins’ shapes. But solving a protein structure is a challenging ...

Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new ...

Researchers at Ben-Gurion University of the Negev have identified simple rules that explain how complex protein structures ...

Syracuse University scientists learned how a flexible, reshaping protein creates temporary sorting and storing centers in stressed cells to potentially protect their health. A companion study found ...

This important paper substantially advances our understanding of how Molidustat may work, beyond its canonical role, by identifying its therapeutic targets in cancer. This study presents a compelling ...