Karpathy shares 'LLM Knowledge Base' architecture that bypasses RAG with an evolving markdown library maintained by AI

Karpathy proposes something simpler and more loosely, messily elegant than the typical enterprise solution of a vector ...
IEEE

Novel Immutable Data Provenance in Embedded Systems: Integrating Critical Infrastructure Auditability and Monitoring via Anonymous Blockchain Technology

Abstract: Embedded systems are at the heart of critical infrastructure facilities in areas such as energy, transportation, healthcare, defense; where integrity, traceability, and auditability of data ...
Business Insider

Structure Therapeutics Reports Positive Topline Data from Phase 2 ACCESS II Trial with Once-Daily Oral Small Molecule GLP-1 Receptor Agonist, Aleniglipron

Placebo-adjusted mean weight loss of 16.3% (39 lbs) at 180 mg and 16.0% (37 lbs) at 240 mg at 44 weeks with no evidence of weight loss plateau in ACCESS II, demonstrating highest efficacy among oral ...
IEEE

Addressing Glaucoma Structure-Function Relationship: A Multi-Task Learning Framework With Multi-Modal and Unpaired Data

Abstract: Glaucoma, an irreversible neurodegenerative disorder, can lead to vision loss and blindness. Visual field (VF) tests are crucial for quantifying functional damage in glaucoma, but the tests ...
GitHub

immutable-ledger

High-speed cryptographic liability scanner for WORM compliance. Evaluates data gravity, identifies missing Ed25519 sidecars, and calculates exposure risk against SEC 17a-4 and ESIC chain-of-custody ...