A team of chemists at the Korea Advanced Institute of Science and Technology has succeeded in pulling an oxygen atom from a molecule and replacing it with a nitrogen atom. In their study, published in ...
The development of new drugs or innovative molecular materials with new properties requires specific modification of molecules. Selectivity control in these chemical transformations is one of the main ...
A new reaction cuts nitrogen atoms out of secondary amines with surgical precision. The transformation offers a route to strained structures, such as cyclobutanes (example shown), that can be ...
Another atom-swapping reaction has entered the ring. Yoonsu Park and his team at the Korea Advanced Institute of Science and Technology (KAIST) have devised a light-driven reaction that replaces an ...
An unconventional route for modifying pharmaceutically relevant molecules swaps an atom of carbon for one of nitrogen. The resulting derivatives might open up avenues of research in ...
For years, if you asked the people working to create new pharmaceutical drugs what they wished for, at the top of their lists would be a way to easily replace a carbon atom with a nitrogen atom in a ...
Catalysts with a metal-nitrogen bond can transfer nitrogen to organic molecules. In this process short-lived molecular species are formed, whose properties critically determine the course of the ...