Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

Chromatin remodelers are ATP-dependent motor proteins that dynamically reorganize chromatin architecture, playing essential roles in gene expression, development, and immune function. Dysregulation of ...

This article explains how diet creates sustained epigenetic changes that affect long-term health, disease risk, aging, and ...

Our cells are usually frantically working to sustain life. Part of this work includes dividing, a process that creates more cells to support our growth when we are children or to replace old, worn-out ...

Experiencing multiple acute stresses at the same time, as in natural disasters or mass shootings, can leave lasting memory scars. New research from the University of California, Irvine suggests that ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...